Bioapigyn® vaginal ointment against incontinence

Composition: oil macerates of the plant species: stem and leaf of shepherd ‘s purse (Capsella bursa-pastoris L.), oak bark (Quercus robur L.), oak galls (Quercus infectoria L.), hazel bark (Corylus avellana L.), basil leaves (Ocimum basilicum L.), sage leaves (Salvia officinalis L.), nettle leaves (Urtica diodica L.), areal parts of yarrow (Achillea millefolium L.), marigold flowers (Calendula officinalis L.), cammomile flowers (Matricaria chamomilla L.), areal part of St. John’s Wort (Hypericum perforatum L.), lady’s mantle leaves (Alchemilla vulgaris L.), areal part of thyme (Thymus serpyllum L.), comfrey root (Symphytum officinale L.), plantain leaves (Plantago major L.), olive leaves (Olea europaea L.); essential oils: tea tree (Melaleuca alternifolia), thyme (Timus vulgaris ct. thymol), ravensara (Cinnamomum camphora ct. cineol), palmarosa (Cympobogon martini), oregano (Origanum compactum) and clove (Eugenia caryophyllata); beeswax (Cera alba); honey; glycerol. 100% natural product! No artificial preservatives, hormones, colorants and fragrances!!

Mode of action: the plants like Capsella bursa-pastoris and Urtica diodica induce the contraction of smooth muscles and consequently, enhance both bladder and uterine muscle tonus significantly. The bioactive components extracted from the plants with confirmed uterotonic activity (Matricaria chamomilla, Calendula officinalis, Plantago major, Symphytum officinale, Capsella bursa pastoris, and Hypericum perforatum) also contributed to the improvement of uterine muscle tonus. Besides, the tannins rich plants with well known astringent activity like Quercus robur, Quercus infectoria, Corylus avellana, Ocimum basilicum had also positive effect on vaginal mucosa trough their strong wound healing, anti-inflammatory and antioxidative potential. So, the combination of the bioactive components from the plant extracts and essential oils result with vasoconstrictor and astringent properties, causing contraction, tightening and firming of the smooth muscles of the pelvic floor and consequently, relief of the symptoms of incontinence significantly which has also positive effect on the quality of sexual life. It decreases the progression of gynecological and urological descensus, regenerates and moisturizes the genital tract mucosa, prevents the development of the bacterial and yeast infections, removes the odor of various pathological conditions.

Indications: This ointment is used for the treatment of vaginal conditions such as the syndrome of vaginal relaxation that involves the loss of optimal structure and architecture of the vaginal channel associated with the natural course of aging, childbirth, hormonal imbalance, local trauma, chronic infections that cause a decrease of muscle tonus of the pelvic floor with negative influence on sexual gratification. Another application is in the patients with so called “Vaginal atrophy” that occurs in perimenopause and menopause. The loss of the muscle tonus of the pelvic floor leads to the inability to retain urine while insufficient moisturizing leads to painful sexual intercourse, irritation and frequent infections.

Dosage and administration: Insert app. 2 g of the ointment deep into the vagina with the clean finger or syringe before bedtime. Continue the usage at least 12 weeks of which the first four weeks every night and afterwards, every 2-3 days. This ointment could be also used by asymptomatic women in order to improve sexual gratification. For that purpose, use app. 2 g of the ointment half an hour before intercourse. Also apply the ointment with clean fingers in a thin layer on the outer part of mucous membranes of the genital tract.

Precautions: Do not use during the pregnancy and breastfeeding. The recommended daily dose must not be exceeded. Do not use in case of hypersensitivity to any component of the product.

Storage instructions: at the temperature between 8oC and 25oC, out of the reach of children.

Packaging: 50 mL box.

Formulated by: prof. dr. sc. Višnja Oreščanin

Patent: HRP20171234A

More informations about the product: Oreščanin V, Findri Guštek Š. Development and Testing of New Herbal Ointment for the Treatment of Stress Urinary Incontinence-A Preliminary Study. Global J Res Anal 1016;5(7):371-374.