Composition: oil macerates of the plant species: marigold flowers (Calendula officinalis L.), plantain leaves (Plantago major L.), chamomile flowers (Matricaria chamomilla L.), aerial part of St. John’s Wort (Hypericum perforatum L.), comfrey root (Symphytum officinale L.), lavender flowers (Lavandula officinalis L.), aerial part of yarrow (Achillea millefolium L.), aerial part of wild thyme (Thymus serpyllum L.), aerial part of sage (Salvia officinalis L.), mint leaves (Mentha piperita L.), lady’s mantle leaves (Alchemilla vulgaris L.), olive leaves (Olea europaea L.); essential oils: tea tree (Melaleuca alternifolia), thyme (Timus vulgaris) ct. thymol, ravensara (Cinnamomum camphora ct. cineol), palmarosa (Cympobogon martini), oregano (Origanum compactum) and clove (Eugenia caryophyllata); beeswax (Cera flava); honey; glycerol. 100% natural product!!! No artificial preservatives, colorants and fragrances!!!
Mode of action: The additive and synergistic effects of bioactive compounds from the oil macerates and essential oils of the selected medicinal plants result in the antimicrobial and anti-viral activity, anti-inflammatory effect as well as positive effect on wound healing and re-epithelialization of the cervical cells. Oil macerates and essential oils maintain a favorable micro-climate of the vagina due to the prevention of dryness of the mucous membranes and creation of the protective layer. The product is soluble at body temperature ensuring excellent coating of the genital tract mucosa and prevents irritation. Addition of 20% of honey in the ointment helps to maintain healthy balance of the vaginal flora due to its antimicrobial, prebiotic and probiotic effect. The components, honey and glycerin used in the given proportions provides optimum moisture of the membranes of the genital tract. Beeswax provides a protective layer on the walls of the outer and inner parts of the genital tract. The oil extracts and essential oils also have a deodorizing effect which removes the odor of some pathological conditions.
Indications: Bioapigyn® ointment is intended for use as a primary therapy for the treatment of cervical metaplasia, as additional therapy in the treatment of cervical intraepithelial neoplasia, as a primary therapy for the prevention of antibiotic’s associated fungal infections, for the treatment of wounds after surgery, childbirth and radiation therapy, for the treatment of the existing fungal infection caused by Candida species, as primary or additional therapy for the treatment of bacterial vaginosis, as additional therapy for the treatment of the infections of the female lower genital tract caused by Ureaplasma, Mycoplasma and Chlamydia, as additional therapy in the treatment of HPV infection and genital herpes. The ointment is also intended for relieve of the symptoms such as itching, vaginal discharge, vaginal dryness and unpleasant odor. It is ideal for the treatment of atrophic changes, and vaginal dryness of perimenopausal and menopausal women.
Dosage and administration: Bioapigyn® ointment is intended for internal and external use on the mucous membranes of the genital tract. Apply a thin layer of the ointment to the external part of the genitals twice a day. If used internally, apply the ointment deep into the vagina once a day, best before bedtime. For the treatment of cervical metaplasia and bacterial vaginosis, use the ointment once a day for two weeks. For the prevention of antibiotics’ associated yeast infection use the ointment during the taking antibiotics’ therapy. To relieve menopausal symptoms use the ointment where necessary. For all other indications use the ointment at least 30 days.
Precautions: Do not use during the pregnancy and breast-feeding. The recommended daily dose must not be exceeded. Do not use in case of hypersensitivity to any component of the product.
Storage instructions: at the temperature between 8oC and 25oC, out of the reach of children.
Packaging: 50 mL
Expiry date: printed on the box and it refers to the originally sealed and properly stored product.
Formulated by: prof. dr. sc. Višnja Oreščanin
Patent: HR: P20150876A